The Eagles (vs. Giants), Chargers (@ Texans), Bengals (vs. Ravens), 49ers (@ Titans), Saints (vs. Dolphins), and Seahawks (vs. Bears) are all owned in about 50 percent of leagues and have solid matchups this week. The Saints are the riskiest, but they always have more upside at home. Even the consistently stellar Colts (@ Cardinals) aren’t widely owned, and despite a tough matchup, they’ve proven they can produce in any matchup. 

WEEK 16 STANDARD RANKINGS:Quarterback | Running back | Wide receiver | Tight end | Kicker

If you really want to trust the stats, you can go with both sides of the Lions-Falcons and Jaguars-Jets games. None of these D/STs have done much of anything this year (though both the Lions and Jets are coming off big weeks), but all have top-10 matchups. If we had to pick one, the Jets have the most upside, but it’s worth noting the Jaguars played a bit better last week without Urban Meyer calling the shots, and Lions have been playing better lately, too. Still, you’d have to be pretty desperate (or in a very deep league) to consider one of these units with so many other potential streamers available.

WEEK 16 PPR RANKINGS:Quarterback | Running back | Wide receiver | Tight end |  Kicker

In addition to being a solid week for streamers, it’s a good week for some of the most reliable defenses. The Cardinals (vs. Colts) have the most worrisome matchup among the top D/STs, but they can still be started because Carson Wentz is prone to mistakes. If Arizona can force Indianapolis into more passing situations than New England did last week, they can still pay off despite how mediocre they looked in a premium matchup against Detroit. The Steelers (@ Chiefs) and Ravens (@ Bengals) are still highly owned but look like stayaways this week.

WEEK 16 FANTASY: Sleepers | Busts | Start ’em, sit ’em

More D/ST options will likely emerge throughout the week, especially if any QBs wind up on the injured/COVID lists. This can work the other way, too, if a team’s defense is decimated by ailing players. Keep track of all the updates, and be prepared to hit the free agent wire. You might have a solid D/ST, but there also might be a better option available. At this point in the season, every point matters. 

WEEK 16 DFS LINEUPS: DraftKings | FanDuel | Yahoo

Note: We’ll be updating these D/ST rankings throughout the week, so check back for the latest analysis and player movement.

Fantasy Defense Rankings Week 16: Who to start, sit at D/ST in fantasy football